5-Fluoro-o-toluoyl chloride

5-Fluoro-o-toluoyl chloride - Names and Identifiers

Name	5-fluoro-2-methylbenzoyl chloride
Synonyms	LIXI-004 5-Fluoro-2-methylbenzoyl 5-Fluoro-o-toluoyl chloride 5-FLUORO-2-METHYLBENZOYL CHLORIDE 2-Methyl-5-fluorobenzoyl chloride 5-fluoro-2-methylbenzoyl chloride
CAS	21900-39-0
EINECS	246-331-6
InChI	InChI=1/C8H6ClFO/c1-5-2-3-6(10)4-7(5)8(9)11/h2-4H,1H3

5-Fluoro-o-toluoyl chloride - Physico-chemical Properties

Molecular Formula	C8H6ClFO
Molar Mass	172.58
Density	1.270 g/mL at 25 °C (lit.)
Boling Point	108 °C/24 mmHg (lit.)
Flash Point	188°F
Vapor Presure	0.178mmHg at 25°C
BRN	2574820
Storage Condition	Keep Cold
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.532(lit.)
MDL	MFCD00236681

5-Fluoro-o-toluoyl chloride - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

5-Fluoro-o-toluoyl chloride - Introduction

chloride is a chemical substance whose chemical formula is C8H6ClFO. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: chloride is a colorless to light yellow liquid.
-Solubility: It is soluble in most organic solvents, such as ethanol, chloroform and ether.
-Melting point and boiling point: The melting point of the compound is about 33-34 degrees Celsius, and the boiling point is about 169-170 degrees Celsius.
-Density: Its density is about 1.27 g/mL.

Use: chloride is mainly used as a reaction reagent in organic synthesis. It can participate in esterification, acylation, coupling reaction and other chemical reactions.
-In addition, it can also be used in the process of research and development of new drugs.

Method:
-and chloride can be prepared by reacting 5-fluoro-2-methylbenzoic acid with thionyl chloride. The reaction is generally carried out at room temperature and protected under an inert atmosphere.

Safety Information: chloride is a corrosive chemical that may cause irritation to the eyes, skin and respiratory system. Appropriate protective equipment such as gloves, goggles and masks should be worn during use.
-It should be kept away from fire and high temperature, and stored in a sealed container, away from oxidants.
-Use with caution to prevent reaction with other chemicals. During use, storage and disposal, please follow the relevant safety procedures and regulations.

Last Update：2024-04-09 02:00:44